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Unformatted text preview: Molecular Genetics BSCI410 Lectures 19-25. Model Organisms Homework due Dec. 2 The final exam will be given on Monday, December 13 at 8:00 am As usual, we want hard copy. This homework covers lectures 19-23. Half of the points on the final exam will come from lectures 19-25. The other half of the points are comprehensive. Review material for the earlier sections was provided on earlier homeworks and review sheets. A complete review sheet for lectures 19-25 will be distributed later. HOMEWORK QUESTIONS You have isolated a new recessive lethal mutation in Drosophila . You tentatively name the mutation (and the gene it's in, unless this mutation turns out to be in previously named gene) hjm in honor of the geneticist H.J. Muller, because of the phenotype of the dead embryos, which have an overgrowth of the central nervous system. You have mapped hjm to the second chromosome, and wish to refine its map position further. To do this, you use cinnabar ( cn , which has a recessive cinnabar eye color phenotype) and curved ( c , which has the recessive phenotype that the wings are curved). You cross hjm / SM5 females ( SM5 is a balancer chromosome for second chromosome) to cn c males, and then mate virgin heterozygous G1 hjm / cn c females to cn c homozygotes. You then examine and test male G2 files that carry a (potentially) recombinant chromosome over the cn c tester chromosome. (recomb. / tester chromosome....
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