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HW1_Answers - D 1/6 II-2 is a carrier to the chance they...

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HW1 BSCI410 Molecular genetics Answer Sheet V.1.1 TB 1. D 2. A and D 3. A. Pink is completely dominant to red B. 4/9 C. ¼ 4. A. Autosomal recessive. I-3 and I-4 do not have cutis laxa but II-4 does, indicating the mode of inheritance is recessive. B. 100%. The individual mothers is affected with an autosomal recessive condition, which means that all her offspring will at least be carriers. C. 2/3. Both parents are carriers since they give rise to an affected progeny. Assuming Mendelian inheritance we expect a ratio of 1:2:1. The II-3 is not affected so these ratio shifts to 1:2 or 2/3 chance II-3 is a carrier.
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Unformatted text preview: D. 1/6. II-2 is a carrier to the chance they pass on a mutant allele is ½, the probability II-3 is a carrier is 2/3 and the probability they would pass on a mutant allele is 2/3*1/2 = 2/6. 2/6*1/2= 1/6. 5. A. 27/64 B. 1/64 C. 9/64 6. A. ascertainment bias B. 43% of the study population will be affected 7. A. 9.02% B. 14.3% C. 9.02% D. 0.2cM 8. A. 12% B. 19cM (Perkins) or 13.7cM (Mapping function). The RF and map distance are different because the former is an observed rate and the latter is an estimate. 9. 43.56% 10. 6*10^11...
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