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Unformatted text preview: Most common secondary structures: -helix, -strand, turns and loops Tertiary Structure The 3 dimensional arrangement of secondary structure elements Quaternary Structure The arrangement of multiple folded protein molecules (or protein subunits) into a functional multi-subunit complex Molecular Chaperones A proteins that guide the folding of many proteins Abnormally folded proteins aggregate and cause human disease Huntingtons Disease Alpha 1-antitrypsin deficiency Prion diseases Gene: IT15 Contains repeats of CAG CAG codes for the amino acid glutamine Many glutamines in a row cause protein aggregation...
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