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Unformatted text preview: A mutated proto-oncogene Mutated proteins no longer properly regulate cell division Capable of causing cancer Over-stimulate cell division Genes involved in regulation of the cell cycle: Genes that halt cell division Tumor suppressor gene Encode proteins that normally stop cell division when conditions are not favorable Key Points Cancer cells are different from normal cells Telomeres protect chromosome ends and limit the number of cell divisions Telomerase extends telomere DNA Cell cycle checkpoints ensure that the stages of the cell cycle are completed properly before continuing to divide Proto-oncogenes and tumor suppressor genes regulate the cell cycle These regulatory genes are often mutated in cancer cells...
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This note was uploaded on 11/08/2011 for the course BIO 0815 taught by Professor Crucielli during the Spring '11 term at Pittsburgh.
- Spring '11
- Cell Cycle