chapter10 Mitosis and meiosis revised 2011

chapter10 Mitosis and meiosis revised 2011 - Chromosomes,...

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Chromosomes, major carriers of genetic information, and the Cell Cycle Chapter 10
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Eukaryotic cells Multiple chromosomes DNA is 1000 x that in a bacterium Hu sperm contain 3 x 10(9) base pairs (haploid);1m long and fits into a nucleus that is 10um This much DNA has to be finely packaged into nucleus accomplished by nucleosome units
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DNA plus protein = chromatin In eukaryotic cells, chromatin is folded and packaged but only condenses into individual chromosomes at mitosis: Number of chromosomes per animal species vary greatly A diploid Hu cell has ~46 chromosomes (ex. aneuploidy) containing 3 billion base pairs
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Nucleosomes Fig 10-2,3: Removal of histone proteins uncoils DNA
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Fig 10-1,4: Chromosome Organization
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Fig 10-5: Eukaryotic Cell Cycle
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Interphase (11.5 hr) Fig 10-6a First gap phase ( G1: 5h) Synthesis phase ( S: 4.5h) Second gap phase ( G2: 2h )
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Centrosome (MTOC) Each MTOC is situated close to the nucleus during interphase Duplicated in G2 Ref: Fundamentals of Cell Bio Centrioles
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Fig 10-7: Chromosome duplicates in S phase academic.brookl yn.cuny.edu/biol ogy/bio4fv/pag. ..
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This note was uploaded on 11/09/2011 for the course BIO 101 taught by Professor Martin during the Fall '08 term at Rutgers.

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chapter10 Mitosis and meiosis revised 2011 - Chromosomes,...

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