slides handout lecture 3 Mitosis Chapter 10

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Unformatted text preview: General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Nucleus
 Mitosis 1
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Outline
 Chapter 10. Chromosomes, mitosis and meiosis. p., 213-223. 1. Cell division and Cell cycle in Eukaryotes 2. Cell cycle: - Interphase: G1, S phase and G2 - M Phase: Mitosis (prophase, metaphase, anaphase, telophse - Cytokinesis: differences in animal and plant cells 3. Cell cycle regulation 4. Prokaryotes: binary fission Review terminology: Genetic material, DNA vs Chromatin and nucleosome. Compare: chromosome, chromatid and sister chromatids. Haploid and diploid cells. 2
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Biosphere
 Living
systems
show

 hierarchical
organization
 3
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Organization of a eukaryotic chromosome 
 1400
nm
 700
nm
 300
nm
fiber
 (looped
 domains)
 3nd
level
 30
nm
chromatin
fiber
 Condensed
 chromosome
 DNA
wound
 around
a
cluster
 of
histone
 molecules
 Scaffolding
 Condensed
chromatin
 protein
 Extended
chromatin
 2nd
level
 Packed
nucleosomes
 10
nm
 Histone
 1st
level
of
organization
 Nucleosomes
 2
nm
 DNA
double
helix
 Fig.
10‐4,
p.
216
 The
cell
division
and
the
cell
cycle
 Cell
cycle
divided
into:
 1. Interphase a. G1 b. S 
 
 
c.
G2
 2. M phase 
 
a. Mitosis b. Cytokinesis 5
 Three
Phases
of
Interphase
 •  G1
phase

 •  S
phase
(synthesis
phase)
 •  G2
phase
 M
Phase
 •  M
phase

 
 
Mitosis
 
 
Cytokinesis
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Prophase
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Metaphase
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 ANAPHASE
 Anaphase
 Telophase
 Cleavage
furrow
 Daughter
chromosomes
 Re‐forming
nuclear
envelope
 Fig.
10‐6e,
p.
219 The
phases
of
cell
cycle
in
plant
cell
 11
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Cytokinesis‐animal
cell
 Cleavage
 furrow
 Actomyosin
 contractile
ring
 10
μm
 Fig. 10-11 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Cytokinesis‐plant
cell
 Small
vesicles
 fuse,
forming
 Vesicles
gather
on
 larger
vesicles
 cell’s
midplane
 Plasma
 membrane
 Cell
 wall
 Cell
plate
 forming
 Eventually
one
 large
vesicle
 exists
 New
cell
walls
 (from
vesicle
 contents)
 New
plasma
 membranes
(from
 vesicle
 membranes)
 Nucleus
 Cell
plate
 forming
 5
μm
 Fig.
10.11
 Cell
Cycle
Checkpoints
 1
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 G1
to
S:

 3
 G2
to
M:


 2
 Metaphase
 to
anaphase:
 http://www.di.uq.edu.au/
 General
Biology
01:119:101‐Fall
2011
 Dr.
Monica
Torres
 Prokaryotes‐
binary
fission
 15
 ...
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