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slides handout Lecture 6 chapter 5 - Outline General...

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Unformatted text preview: Outline General Biology 01:119:101-Fall 2011 Dr. Monica Torres Biological membranes. Chapter 5, pp. 106-130 - Structure: fluid mosaic fluid, phospholipids and proteins - Permeability - Transport across membrane - Simple diffusion, facilitated diffusion, osmosis -  Facilitated diffusion -  Carrier-mediated active transport (Na+/K+ and proton pump) -  Transport of large molecules: Exocytosis, Endocytosis, 1
 Phagocytosis, Pinocytosis General Biology 01:119:101-Fall 2011 Dr. Monica Torres Integral

protein
 Phospholipid

 bilayer
 Peripheral
protein
 Fig.
5‐2b,
p.
108
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Membrane
fluidity
 Lateral
 movement
 only
 Time
 Fig.
5‐4,
p.
109
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Integral
Proteins

 Peripheral

Proteins

 Ions
 water
 Ions
 water
 Fig.
5.7.,
p.111,

see
also
Fig
5‐10
 Synthesis
and
orientation
of
a
membrane
protein.

 Nucleus
 Rough
ER
 1
 Transport
vesicle
 2
 Golgi
complex
 Plasma
 membrane
of
 cell
 Membrane
of
Golgi
 complex
 Transport
vesicle
 Carbohydrate
chain
 3
 Plasma
membrane
 4
 Fig.
5‐9,
p.
113
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres What
substances
readily
diffuse
across
a
lipid
bilayer?
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres What
cannot
diffuse
readily
across
a
lipid
bilayer?
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Passive
and
active
transport
in
cell
membranes
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Passive
and
active
transport
in
cell
membranes
 O2,

 CO2
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Diffusion

 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Facilitated diffusion: Channel proteins General Biology 01:119:101-Fall 2011 Dr. Monica Torres Facilitated
Diffusion:
protein
carrier
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres 
Osmosis
 Fig 5.12 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Solutions
 Water
Balance
of
animal
and
plant
cells
 Hypotonic
solution H2O Isotonic
solution Hypertonic
solution H2O H2O H2O (a)
Animal
 cell Lysed H2O Normal H2O Shriveled H2O H2O (b)
Plant
 cell Turgid
(normal) Flaccid Plasmolyzed The
sodium–potassium
pump


 Higher
 Outside
 cell
 Lower
 Sodium
 concentration
gradient
 Potassium
 concentration
gradient
 Active
 transport
 channel
 Lower
 Cytosol
 Higher
 Fig.
5‐17a,
p.
121
 A
Carrier–mediated
active
transport:
Proton
Pump
 Fig. 5.18 Endocytosis
(Phagocytosis)
 
Exocytosis
 1
 Vesicle
approaches

 plasma
membrane,
 2
 fuses
with
it,
and
 3
 releases
its
contents
outside
 cell.
 Fig.
5‐20a,
p.
124
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Receptor‐Mediated
Endocytosis
 Fig. 5.23 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Desmosomes
 Plasma
 membranes
 Intercellular
 space
 Intermediate
 filaments
 Protein
 filaments
 Disc
of

 dense
protein
 material
 Desmosome
 Cell
1
 Cell
2
 Fig.
5‐24,
p.
 127
 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Tight
Junctions
 Fig. 5.25 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Gap
Junctions
 Fig. 5.26 General Biology 01:119:101-Fall 2011 Dr. Monica Torres Plasmodesmata
 Fig. 5.27 ...
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