3MembranePermeability.ppt

3MembranePermeability.ppt - 8/31/10 Membrane Permeability...

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8/31/10 1 Membrane Permeability Summary from Previous Lecture • Neurons generate electrical signals by altering membrane potential • These alterations are accomplished by varying the permeability of the membrane to sodium and potassium
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8/31/10 2 The question is • How are the changes in membrane permeability accomplished? • Hint: In order for an action potential to be initiated, the membrane must be brought to threshold.
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8/31/10 3 Voltage-dependent Membrane Permeability • Practical considerations – Measuring current through voltage- dependent channels – Voltage clamp
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8/31/10 4 Voltage-dependent permeability
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8/31/10 5 Identifying Responsible Currents • Based on considerations of the Nernst Equation Identifying Responsible Currents • Based on considerations of the Nernst Equation
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6 Identifying Responsible Currents • Based on manipulating the ionic environment Identifying Responsible Currents • Based on manipulating the ionic environment
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This note was uploaded on 11/09/2011 for the course CHEM 2341 taught by Professor Staff during the Fall '11 term at Texas State.

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3MembranePermeability.ppt - 8/31/10 Membrane Permeability...

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