3MembranePermeabilityTRACS

3MembranePermeabilityTRACS - Membrane Permeability Summary...

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Membrane Permeability
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Summary from Previous Lecture Neurons generate electrical signals by altering membrane potential These alterations are accomplished by varying the permeability of the membrane to sodium and potassium
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The question is How are the changes in membrane permeability accomplished? Hint: In order for an action potential to be initiated, the membrane must be brought to threshold.
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Voltage-dependent Membrane Permeability Practical considerations Measuring current through voltage- dependent channels Voltage clamp
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Voltage-dependent permeability
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Identifying Responsible Currents Based on considerations of the Nernst Equation
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Identifying Responsible Currents Based on manipulating the ionic environment
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Identifying the Responsible Currents Pharmacologically Tetrodotoxin = sodium channel blocker Tetraethylammonium (TEA) = potassium channel blocker
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The Relationship between Current and Potential Considerations based on Nernst equation
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Relationship between V m and Conductance
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This note was uploaded on 11/09/2011 for the course CHEM 2341 taught by Professor Staff during the Fall '11 term at Texas State.

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3MembranePermeabilityTRACS - Membrane Permeability Summary...

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