7NeurotransmittersTRACS

7NeurotransmittersTRACS - Neurotransmitters What you should...

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Neurotransmitters
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What you should know Defining characteristics Classes of neurotransmitters (NTs) Specific examples of well studied NTs (and to which classes they belong) A little bit about NT metabolism for specific examples A little bit about drugs and their FX
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Neurotransmitters must be present within presynaptic neuron must be released in response to presynaptic depolarization; release must be Ca 2+ -dependent specific receptors for NT must be present on post-synaptic cell
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Classes of Neurotransmitter Small molecule neurotransmitters Diverse molecules (more detail to follow) Typically synthesized in the synaptic bouton Packaged in small, electron-lucent vesicles Neuropeptides 3-36 aa’s in length Synthesized in the nerve cell body Packaged in larger, electon-dense vesicles
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Small Molecule NTs Acetylcholine Amino Acid NTs Glutamate Glycine Aspartate GABA (gamma amino butyric acid) Purines - ATP
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This note was uploaded on 11/09/2011 for the course CHEM 2341 taught by Professor Staff during the Fall '11 term at Texas State.

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7NeurotransmittersTRACS - Neurotransmitters What you should...

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