Intro.ppt - Astrocytes Oligodendrocytes/ Schwann cells...

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Neuroscience • Effort and approach to understanding the nervous system • Based on results obtained from – Genetics – Mol bio Cell bio – Anatomy – Physiology – Behavioral studies – psychology
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(Y)our challenge • “to integrate the diverse knowledge derived from these various levels of analysis into a more or less coherent understanding of brain structure and function .”
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Course Emphasis •Human •CNS •Cellular and molecular neurobiology
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Today’s Goals • Introduce and give overview of nervous system and organs comprising it • Introduce cells comprising nervous system
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Nervous System •What is it? –Anatomical •What does it do? –Functional
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Anatomical Divisions • Central Nervous System –Brain (including retina) –Spinal cord • Peripheral Nervous System –Everything else
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Functional Divisions •Sensory Systems •Motor Systems
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Cellular Components of Nervous System • Glia
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Unformatted text preview: Astrocytes Oligodendrocytes/ Schwann cells Microglia Ependyma Neurons Astrocytes Function Maintain chemical balance in ECF of CNS Neurochemical recycling Formation of BBB Astrocytes in tissue culture Oligodendrocytes and Schwann Cells Myelinate axons Microglia Immune cells of CNS Phagocytic Cytokine-secreting Modulate inflammation and cell death Ependyma Secrete cerebrospinal fluid Participate in formation of BBB Neurons Morphology Regular cellular features Neuron-specific features Axons Dendrites Special nomenclature, e.g. soma Typical neuron Morphologic Diversity Overall function of Neurons/ Nervous System Take in information Integrate it Generate output Neuronal Circuits Simple reflex circuit Afferent Efferent More complexity Interneurons Still more complexity...
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Intro.ppt - Astrocytes Oligodendrocytes/ Schwann cells...

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