Enzymes - The substrate molecule normally does not fit...

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Enzymes What Are Enzymes? Substances that speed up chemical reactions are called catalysts . Organic catalysts are called enzymes . Enzymes are specific for one particular reaction or group of related reactions. Many reactions cannot occur without the correct enzyme present. They are often named by adding "ase" to the name of the substrate. Example: Dehydrogenases are enzymes that remove hydrogen. Induced-Fit Theory An enzyme-substrate complex forms when the enzyme’s active site binds with the substrate like a key fitting a lock. The shape of the enzyme must match the shape of the substrate. Enzymes are therefore very specific; they will only function correctly if the shape of the substrate matches the active site.
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Unformatted text preview: The substrate molecule normally does not fit exactly in the active site. This induces a change in the enzymes conformation (shape) to make a closer fit. In reactions that involve breaking bonds, the inexact fit puts stress on certain bonds of the substrate. This lowers the amount of energy needed to break them. The enzyme does not form a chemical bond with the substrate. After the reaction, the products are released and the enzyme returns to its normal shape. Because the enzyme does not form chemical bonds with the substrate, it remains unchanged. As a result, the enzyme molecule can be reused. Only a small amount of enzyme is needed because they can be used repeatedly....
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This note was uploaded on 11/10/2011 for the course BIOLOGY bi 101 taught by Professor - during the Fall '10 term at Montgomery.

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Enzymes - The substrate molecule normally does not fit...

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