Figure41 - clot. The healthy endothelial tissue that...

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Figure 1. The Clotting Process Following its formation, a clot is further strengthened by a process called clot retraction. Platelets in the clot contract, pulling on the fibrin strands to which they are attached. The result is a more tightly sealed patch. Fibrinolysis is the breakdown of the clot as the damaged blood vessel is repaired. During the formation of a clot, the plasma protein plasminogen is incorporated into the
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Unformatted text preview: clot. The healthy endothelial tissue that replaces the damaged areas of the blood vessel secretes tissue plasminogen activator (t-PA), which converts plasminogen into its active form, plasmin (fibrinolysin). Plasmin in turn breaks down fibrin and leads to the dissolution of the clot....
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