Lymphocytes

Lymphocytes - Lymphocytes

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Lymphocytes The primary agents of the immune response are lymphocytes, white blood cells (leukocytes) that  originate in the bone marrow (like all blood cells) but concentrate in lymphoid tissues such as the  lymph nodes, the thymus gland, and the spleen. When lymphocytes mature, they become  immunocompetent, or capable of binding with a specific antigen. An immunocompetent lymphocyte  displays unique proteins on its plasma membrane that act as antigen receptors. Because all of the  antigen receptors of an individual lymphocyte are identical, only a specific antigen can bind to an  individual lymphocyte. The kind of antigen receptors displayed by a particular lymphocyte is  determined by somatic recombination, a shuffling of gene segments during lymphocyte maturation.  By mixing gene segments, more than one billion different antigen receptors can be generated. Here are the various kinds of lymphocytes: 
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This note was uploaded on 11/10/2011 for the course PT 101 taught by Professor Staff during the Spring '10 term at Texas State.

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