umcg2

umcg2 - Multi-scale modeling of the carotid artery G....

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University of Groningen Multi-scale modeling of the carotid artery G. Rozema, A.E.P. Veldman, N.M. Maurits University of Groningen, University Medical Center Groningen The Netherlands

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University of Groningen ACC: common carotid artery ACE: external carotid artery ACI: internal carotid artery distal proximal Area of interest Atherosclerosis in the carotid arteries is a major cause of ischemic strokes!
University of Groningen A model for the local blood flow in the region of interest: A model for the fluid dynamics: ComFlo A model for the wall dynamics A model for the global cardiovascular circulation outside the region of interest (better boundary conditions) Multi-scale modeling of the carotid artery Several submodels of different length- and timescales Carotid bifurcation Fluid dynamics Wall dynamics Global Cardiovascular Circulation (electric network model)

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University of Groningen Computational fluid dynamics: ComFlo Finite-volume discretization of Navier-Stokes equations Cartesian Cut Cells method Domain covered with Cartesian grid Elastic wall moves freely through grid Discretization using apertures in cut cells Example: Continuity equation Conservation of mass:
University of Groningen Modeling the wall as a mass-spring system The wall is covered with pointmasses (markers) The markers are connected with springs For each marker a momentum equation is applied x : the vector of marker positions

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University of Groningen Boundary conditions Simple boundary conditions: Dynamic boundary conditions: Deriving boundary
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This note was uploaded on 11/11/2011 for the course MATH 220 taught by Professor Kearn during the Fall '11 term at BYU.

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umcg2 - Multi-scale modeling of the carotid artery G....

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