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Unformatted text preview: The antibodies involved in anaphylaxis reactions are of the type IgE. In cytotoxic and immune complex reactions, IgG and IgM are involved. Anaphylaxis. Anaphylaxis, or type I hypersensitivity, is a whole-body, immediate hypersensitivity also known as anaphylactic shock. The allergens are introduced to the body directly to the tissues in a concentrated form (intramuscular or intravenous injection, for example). After the sensitizing dose has been administered, IgE is produced by the plasma cells. The antibodies circulate in the blood and attach at the Fc end to mast cells of the tissues and basophils in the bloodstream (Figure 1 ). This activity occurs during the latent period. When the eliciting dose of allergen is later administered, the antigens combine with antibodies on the surface of the mast cells and basophils....
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- Fall '07