epileps1

epileps1 - Epilepsy data after some manipulation to get...

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Epilepsy data after some manipulation to get them in shape for analysis 1 First 12 observations b s a e p l l t s i l o l o r e z a t t t t g o g t l u t c p i i i i b g s t O i r i t a e r m m m m a a e i b i n e m r g b o e e e e s g i m s d e s e t e o g 1 2 3 4 e e z e 1 104 2.75 5 1 0 31 1 0 1 0 0 0 1.01160 3.43399 1.79176 01 2 106 2.75 3 1 0 30 1 0 1 0 0 0 1.01160 3.40120 1.38629 01 3 107 1.50 2 1 0 25 1 0 1 0 0 0 0.40547 3.21888 1.09861 01 4 114 2.00 4 1 0 36 1 0 1 0 0 0 0.69315 3.58352 1.60944 01 5 116 16.50 7 1 0 22 1 0 1 0 0 0 2.80336 3.09104 2.07944 01 6 118 6.75 5 1 0 29 1 0 1 0 0 0 1.90954 3.36730 1.79176 01 7 123 3.00 6 1 0 31 1 0 1 0 0 0 1.09861 3.43399 1.94591 01 8 126 13.00 40 1 0 42 1 0 1 0 0 0 2.56495 3.73767 3.71357 01 9 130 5.75 5 1 0 37 1 0 1 0 0 0 1.74920 3.61092 1.79176 01 10 135 2.50 14 1 0 28 1 0 1 0 0 0 0.91629 3.33220 2.70805 01 11 141 13.00 26 1 0 36 1 0 1 0 0 0 2.56495 3.58352 3.29584 01 12 145 8.25 12 1 0 24 1 0 1 0 0 0 2.11021 3.17805 2.56495 01 logseiz 0 1 2 3 4 logbase 01234 Plot of log(seizure count+1) versus log(baseline count/4) Plotted separately for each treatment by time combination trt=0 time=1
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logseiz 0 1 2 3 4 logbase 01234 Plot of log(seizure count+1) versus log(baseline count/4) Plotted separately for each treatment by time combination trt=0 time=2 Some plots omitted to save space. logseiz 0 1 2 3 4 5 logbase Plot of log(seizure count+1) versus log(baseline count/4) Plotted separately for each treatment by time combination trt=1 time=4
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Model 1: GEE-type model fit with independence working correlation matrix 2 The GENMOD Procedure Model Information Data Set WORK.EPILEPS Distribution Poisson Link Function Log Dependent Variable seizures Number of Observations Read 236 Number of Observations Used 236 Class Level Information Class Levels Values time 4 1 2 3 4 trt 2 0 1 id 59 101 102 103 104 106 107 108 110 111 112 113 114 116 117 118 121 122 123 124 126 128 129 130 135 137 139 141 143 145 147 201 202 203 204 205 206 207 208 209 210 211 213 214 215 217 218 219 220 221 222 225 226 227 228 230 232 234 236 238 Parameter Information Parameter Effect time trt Prm1 Intercept Prm2 time 1 Prm3 time 2 Prm4 time 3 Prm5 time 4 Prm6 trt 0 Prm7 trt 1 Prm8 time*trt 1 0 Prm9 time*trt 1 1 Prm10 time*trt 2 0 Prm11 time*trt 2 1 Prm12 time*trt 3 0 Prm13 time*trt 3 1 Prm14 time*trt 4 0 Prm15 time*trt 4 1 Prm16 logbase Prm17 logbase*time 1 Prm18 logbase*time 2 Prm19 logbase*time 3 Prm20 logbase*time 4 Prm21 logbase*trt 0 Prm22 logbase*trt 1 Prm23 logbase*time*trt 1 0
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Model 1: GEE-type model fit with independence working correlation matrix 3 The GENMOD Procedure Parameter Information Parameter Effect time trt Prm24 logbase*time*trt 1 1 Prm25 logbase*time*trt 2 0 Prm26 logbase*time*trt 2 1 Prm27 logbase*time*trt 3 0 Prm28 logbase*time*trt 3 1 Prm29 logbase*time*trt 4 0 Prm30 logbase*time*trt 4 1 Algorithm converged. GEE Model Information Correlation Structure Independent Within-Subject Effect time (4 levels) Subject Effect id (59 levels) Number of Clusters 59 Correlation Matrix Dimension 4 Maximum Cluster Size 4 Minimum Cluster Size 4 Algorithm converged. Working Correlation Matrix Col1 Col2 Col3 Col4 Row1 1.0000 0.0000 0.0000 0.0000 Row2 0.0000 1.0000 0.0000 0.0000 Row3 0.0000 0.0000 1.0000 0.0000 Row4 0.0000 0.0000 0.0000 1.0000 GEE Fit Criteria QIC -1242.5523 QICu -1242.3501
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Model 1: GEE-type model fit with independence working correlation matrix 4 The GENMOD Procedure Analysis Of GEE Parameter Estimates Empirical Standard Error Estimates Standard 95% Confidence Parameter Estimate Error Limits Z Pr > |Z|
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epileps1 - Epilepsy data after some manipulation to get...

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