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lec1_green - Economic Incentives Ambient Standards...

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The Health Risk Assessment / Health Risk Management Paradigm Scientific data Problem Formulation Epidemiologic studies Discussions Am ong “Risk ø (Clinical Studies) Assessors,” “ Risk Managers,” and Rodent studies “Stakeholders” Mechanistic experiments Exposure Monitoring Environmental Fate and Risk Assessment ø transport Modeling • Hazard Identification • Dose Response Assessment • Exposure Assessment • Risk Characterization Risk Communication • More Discussions Among Risk Assessors, Risk Managers, and Stakeholders Decision or Action No Action Risk Management Evaluation of Public Health, Social, Economic, Political, Engineering Factors * Information Programs
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Unformatted text preview: Economic Incentives Ambient Standards Pollution Prevention Chemical Substitution Chemical Ban Quantitative Health (Cancer) Risk Assessment: Interpretation, and interpolation. 0% 10% 20% 30% 40% 50% 1 100 1,000 10,000 100,000 / 10 Airborne benzene, micrograms cubic meter Probability of cancer CalEPA Observed MLE UCL95 on MLE Figure 1. Epidemiologic exposure-response (AML) data for benzene. Note that the x-axis is a log-scale. 1.8 1.6 1.4 1.2 1.0 0.8 0.6 1 2 3 4 5 6+ All Cancer Deaths All Deaths Coronary Heart Disease Deaths RATE RATIO DRINKS PER DAY Alcoholic Beverages dose-response curves (Boffetta & Garfinkel, 1990). Figure by MIT OCW....
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