lecture18

lecture18 - 20.106J Systems Microbiology Lecture 18 TA...

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20.106J – Systems Microbiology Lecture 18 TA: Megan McBee ¾ Chapters 22 and 23 ± Innate immunity and inflammation o Cells and organs o Innate response o Signals (chemokines, cytokines) o Inflammation o Adaptive immune response ± Why do we have an immune system? o Vertebrates and mammals have the most developed immune system, with both arms active ± Cells of the immune system o Differentiation starts from bone marrow cells o Today we’ll be talking about polymorphonuclear leukocytes and macrophages ± The immune system can also be called the Lymphatic system o Similar to the circulatory system in that there are vessels that can carry things throughout your body o Lymph nodes ± An overview of the immune response ± Cell characteristics o We’re mainly going to be talking about neutrophils o There are PMN and Monocytes – both are phagocytic ± PRRs – pathogen recognition receptors o Toll-like receptors (TLRs) in mammals ± Monocytes and Neutrophils perform phagocytosis, gobbling up the microbe and
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This note was uploaded on 11/11/2011 for the course BIO 20.010j taught by Professor Lindagriffith during the Spring '06 term at MIT.

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lecture18 - 20.106J Systems Microbiology Lecture 18 TA...

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