lecture19

lecture19 - 20.106J Systems Microbiology Lecture 19 TA:...

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20.106J – Systems Microbiology Lecture 19 TA: Megan McBee ± Adaptive Immunity, Immunization, and Immune Disorders o One of the big things we’ll be talking about interactions between dendritic cells and T-cells/lymphocytes ± Immune response o Innate immunity – interaction with pathogens o Dedritic cells are monophages ± They create a more specific immune response ± This is adaptive immunity ± There are two arms o Antigens ± Molecules that are recognized by antibodies or T-cell receptors ± TCRs ± Antigenic determinant or epitope o Immunoglobin Superfamily ± Class I MHC ± Class II MHC ± T-cell receptor ± Immunoglobulin o Major Histocompatability Complex ± Human leukocyte antigen complex o MHC Proteins ± Class I proteins are expressed on all nucleated cells ± Class I proteins are recognized by T cells ± Class II proteins are expressed only on antigen-presenting cells o MHC-antigen Processing and Presentation o TCR Genes and Diversity ± TCRs bind much more specifically
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This note was uploaded on 11/11/2011 for the course BIO 20.010j taught by Professor Lindagriffith during the Spring '06 term at MIT.

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lecture19 - 20.106J Systems Microbiology Lecture 19 TA:...

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