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slides23 - Animal- and arthropod-transmitted diseases Dec...

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Unformatted text preview: Animal- and arthropod-transmitted diseases Dec 6, 2006 Ch. 27 Galn and Wolf-Watz review Plague Infectious disease of animals and humans Caused by a bacterium named Yersinia pestis People usually get plague from being bitten by a rodent flea that is carrying the plague bacterium Antibiotics are effective against plague, but if an infected person is not treated promptly, the disease is likely to cause illness or death Epidemiology Wild rodents in certain areas are infected with plague Outbreaks usually associated with infected rats and rat fleas ( Xenopsylla cheopis) Globally, the WHO reports 1,000 to 3,000 cases of plague each year http://www.cdc.gov/ncidod/dvbid/plague History of plague First pandemic spread from Egypt to Europe, Africa, and Asia 542-600 Second pandemic known as the Black Death spread from Asia to Europe in the 1300s http://bubonicplague.quickseek.com/ Natural history Epidemics usually involve rats Last rat-borne epidemic in the US occurred in Los Angeles in 1924-25 Since then, all human cases in the U.S. have been sporadic cases acquired from wild rodents Rock squirrels and their fleas are the most frequent sources of human infection in the southwestern states www.mammalogy.org Courtesy of Diliff. Geographic distribution Averages about 18 cases per year in US Mostly in people < 20 years of age About 1 in 7 persons will die Epidemic plague occurs Africa, Asia, & South America associated with domestic rats Forms of disease...
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This note was uploaded on 11/11/2011 for the course BIO 20.010j taught by Professor Lindagriffith during the Spring '06 term at MIT.

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slides23 - Animal- and arthropod-transmitted diseases Dec...

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