hw1_soln

hw1_soln - MIT 2.782J/3.961J/BEH.451J/HST524J Spring 2006...

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MIT 2.782J/3.961J/BEH.451J/HST524J Spring 2006 DESIGN OF MEDICAL DEVICES/IMPLANTS Homework #1 Solutions 1 (50%) Which device components are required? Which are sufficient? a. Insufficient. No scaffold layer or seeded cells provided. b. Insufficient. No silicone film or cell seeding provided. Half-life of scaffold is too long. c. Insufficient. For “simultaneous regeneration of dermis and epidermis”, as specified in problem statement, you need scaffold “f” but there is also requirement for seeding with keratinocytes (KC). d. Silicone required. e. Synthetic polymers have not so far been shown to have regenerative activity. KC seeding is also missing. f. The scaffold is OK. Missing: silicone and KC seeding. g. This device is both required and sufficient. h. The scaffold pore size is too large and the half-life is too long. Silicone and KC are missing. i. Fibroblasts are not required. j.
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hw1_soln - MIT 2.782J/3.961J/BEH.451J/HST524J Spring 2006...

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