hw7 - BE.430/2.795/6.561/10.539/HST.544 Homework Set 7...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
BE.430/2.795//6.561/10.539/HST.544 Homework Set 7 Handed out: Monday, Nov. 29, 2004 Due: Monday, Dec. 6 by 5pm
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Problem 1 – Hepatocyte growth factor delivery in a rectangular bioreactor channel filled with cells Consider the model for nutrient delivery and fluid flow through a perfused tissue bioreactor channel developed in class. In that articulation, the channel was lined with a layer of liver tissue cells and allowed the development of a parabolic axial fluid profile in the channel center. Now, instead, consider the perfusion of a very wide, thin, rectangular bioreactor channel filled with a co-culture of vascular endothelial cells and liver tissue cells for delivery of hepatocyte growth factor (HGF). In this case, the HGF concentration profile can be assumed to be distributed across a single rectangular coordinate axis. The tissue co-culture is established by lining the channel walls with liver cells at high density and filling the center with vascular endothelial cells at low density. Due to the presence of the endothelial cells in the channel lumen, the axial fluid
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/11/2011 for the course BIO 20.410j taught by Professor Rogerd.kamm during the Spring '03 term at MIT.

Page1 / 3

hw7 - BE.430/2.795/6.561/10.539/HST.544 Homework Set 7...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online