lec14a_cell_forc

lec14a_cell_forc - Macroscopic forces generated by...

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Unformatted text preview: Macroscopic forces generated by cell-matrix interactions I. Cells generate forces after becoming attached to a matrix. I. Cells generate forces after becoming attached to a matrix. II. How do cells attach to a matrix? III. Cell-matrix interactions control the spontaneous closure of wounds in organs. III. Cell-matrix interactions control the spontaneous closure of wounds in organs. IV. What happens when wound closure occurs by induced regeneration? IV. What happens when wound closure occurs by induced regeneration? Harvard-MIT Division of Health Sciences and Technology HST.523J: Cell-Matrix Mechanics Prof. Ioannis Yannas I. Cells generate forces after becoming attached to a matrix. . Cells develop contractile forces individually, not cooperatively. Cell elongation, not contraction, occurs first, and eventually leads to matrix deformation. Contractile forces are force-limited, not displacement-limited. A brief review or relevant structures: cell membrane, transmembrane proteins, cell receptors (integrins), cytoplasm, matrix Definition of unit cell process Figure by MIT OCW. A typified cell diagram showing cell-cell binding Figure removed for copyright reasons....
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This note was uploaded on 11/11/2011 for the course BIO 20.410j taught by Professor Rogerd.kamm during the Spring '03 term at MIT.

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lec14a_cell_forc - Macroscopic forces generated by...

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