MIT20_441JF09_hw6

MIT20_441JF09_hw6 - 2.79J/3.96J/BEH.441/HST522J...

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2.79J/3.96J/BEH.441/HST522J Biomaterials - Tissue Interactions Homework #6 1a. Three companies have developed competing polymers that they say can result in bonding (chemical bonding) of fibrous tissue to the surface as a result of adhesion of fibronectin (Fn). In support of their claims they provide the following data (Fig. 1.1). Which polymer would you choose to use? Explain. A B C [Fn] Fig. 1.1 1
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on a specific polymer ("D"). It has generated the following data (Figs. 1.2 and 1.3) but cannot explain its behavior. The desorption curve was produced after a residence time of 10 hours. Help this company explain its findings. Desorption D Adsorption [P] Fig. 1.2 Typical adsorption kinetics for all [Pi] 1 hr Time Fig. 1.3 1c. The company with polymer "D" stated that these results show that with increasing time in vivo ( i.e. , increasing residence time) the strength of tissue attachment should increase. Do you agree? 2
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This note was uploaded on 11/11/2011 for the course BIO 20.410j taught by Professor Rogerd.kamm during the Spring '03 term at MIT.

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MIT20_441JF09_hw6 - 2.79J/3.96J/BEH.441/HST522J...

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