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Unformatted text preview: many orientations. Do they all occur with equal frequency among solved protein structures? How do the rare packings differ from the common ones? 2. Are the hydrogen bonding patterns between the strands of the jellyroll fold equivalent for all pairs of strands? If not, where do they differ? 3 Lesk and Chothia compared nine globin proteins of diverse sequence. What were their initial assumptions to explain the conserved three-dimensional structure? What did they find instead?...
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- Spring '08
- Chothia, protein folding problem