7_88_assign4

7_88_assign4 - diagram. Number the strands sequentially...

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MIT OpenCourseWare http://ocw.mit.edu 7.88J Protein Folding Problem Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms .
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The Protein Folding Problem ‘07 Assignment 4 Session 8 Reading: Branden and Tooze: Chapter 15: Immunoglobulin β -sheet folds The functions of the immune system are both profoundly important and scientifically fascinating; however your main task for this course is to become familiar with the folding of the chains of proteins of the immune system. Questions to answer (turn in Session 10): 1. Draw the constant domain of the immunoglobulin IgG in a ribbon or ribbon-like
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Unformatted text preview: diagram. Number the strands sequentially according to their order in the polypeptide chain. 2. Go to the Protein Data Bank, find the structure of an immunoglobulin of interest to you. Print out the variable domain -sheet in a format that reveals the backbone fold. 3. What level of structure (primary, secondary, tertiary, quaternary) is recognized by the MHC antigen binding cleft? By the immunoglobulin CDRs? 4. Write a question for the class on Chapter 15 (Branden & Tooze) and answer it....
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This note was uploaded on 11/11/2011 for the course BIO 7.344 taught by Professor Bobsauer during the Spring '08 term at MIT.

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7_88_assign4 - diagram. Number the strands sequentially...

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