7_88_assign6

7_88_assign6 - determinants of the coiled coil fold. 1...

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MIT OpenCourseWare http://ocw.mit.edu 7.88J Protein Folding Problem Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms .
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The Protein Folding Problem ‘07 Assignment 6 Session 13 Readings Branden and Tooze ; Pages 286-297, Coiled coils and muscles Erin O’Shea, Rheba Rutkowski and Peter S. Kim (1989) Evidence that the Leucine Zipper is a Coiled Coil. Science, 243: 538-542. (available online through MIT Libraries) [NOTE: This is not the X-ray structure paper 1 , but its precursor. The methodology has subsequently been used for ongoing investigations of the sequence
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Unformatted text preview: determinants of the coiled coil fold. 1 (Erin OShea, Juli D. Klem, Peter S. Kim, and Tom Alber (1991). X-ray Structure of the CGN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil. Science, 254: 539-544.)] Questions (turn in Session 15): 1. Identify the ion pairs present or potentially present in the GCN4 structure. 2. Create a single image of the GCN4 (PDB-ID: 2ZTA) structure that shows: a. the backbones of the two coils depicted as ribbons, colored by chain and, b. the inter-helical ion pairs you identified depicted as space-filled models....
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This note was uploaded on 11/11/2011 for the course BIO 7.344 taught by Professor Bobsauer during the Spring '08 term at MIT.

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7_88_assign6 - determinants of the coiled coil fold. 1...

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