7_88_pset

7_88_pset - MIT OpenCourseWare http://ocw.mit.edu 7.88J...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: MIT OpenCourseWare http://ocw.mit.edu 7.88J Protein Folding Problem Fall 2007 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms . 7.24j/7.88j/5.48j/10.543j Fall 2007 Graded Problem Set 1) (20 pts) a) (4 pts) Draw and label the complete structures of the cis and trans prolyl-isomers that may be found at pH 7 for the tripeptide b) (6 pts) Given a polypeptide of 100 amino acids in length, how long would the folded conformation be if: i) (2 pts) Folded into an -helix, as found in globular proteins? ii) (2 pts) Folded into a collagen triple helix? iii) (2 pts) Folded into a -strand? c) (5 pts) What conformation would you predict for the repeated sequence (Ala-Pro-Ser) n in solution? i) An -helix? ii) Collagen-like triple helix? iii) Coiled-coil? iv) Other? d) (5 pts) Which of the above conformations is the following sequence most likely to take in solution, under physiological conditions?...
View Full Document

This note was uploaded on 11/11/2011 for the course BIO 7.344 taught by Professor Bobsauer during the Spring '08 term at MIT.

Page1 / 4

7_88_pset - MIT OpenCourseWare http://ocw.mit.edu 7.88J...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online