l6_notes

l6_notes - Systems Biology ? Systems Biology Network...

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Systems Biology ?
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Systems Biology Network Biology GOAL : develop a quantitative understanding of the biological function of genetic and biochemical networks gene A gene C gene E gene B gene D gene F INPUT OUTPUT - function of gene product A-F can be known in detail but this is not sufficient to reveal the biological function of the INPUT-OUTPUT relation - a system approach (looking beyond one gene/protein) is necessary to reveal the biological function of this whole network - what is the function of the individual interactions (feedbacks and feedforwards) in the context of the entire network ?
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Alternatively, Systems Engineering + Molecular Biology Systems Engineering Molecular Biology Systems Biology = Applying Systems Engineering concepts to Biological Systems
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OR2 OR3 λλ λλ λ λ OR2 OR3 λλ OR2 OR3 λλ λλ K 1 K 2 A traditional molecular biologist would ask: - what is the molecular structure of the cI dimer ? - what is DNA sequence recognized
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l6_notes - Systems Biology ? Systems Biology Network...

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