Lecture5

Lecture5 - Image courtesy of the National Institute on...

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Complicating the model of LTP
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Today’s Papers
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Alzheimer’s disease • Plaques and tangles • Amyloid beta • Phosphorylated tau • Presenilins
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Enzymes act on the APP (Amyloid precursor protein) and cut it into fragments of protein, one of which is called beta-amyloid and its crucial in the formation of senile plaques in Alzheimer. (Image courtesy of the National Institute on Aging .)
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β -Amyloid Plaques Image by MIT OpenCourseWare
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Unformatted text preview: Image courtesy of the National Institute on Aging . Presenilin1-2 Mutations cause high risk for FAD 7 transmembrane proteins May affect Amyloid Beta cleavage Questions for next week Morris when should a cued platform be used? Halagappa et al. How does the experiment described in figure 1 affect the interpretation of the experiments in figures 2-4?...
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Lecture5 - Image courtesy of the National Institute on...

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