Lecture9

Lecture9 - Input 2 Output Tagging Input 1 Input 2 Output...

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Hippocampal representation of space in contextual fear conditioning
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Today’s papers
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Next week – back to LTP • Overview of what we know • L-LTP, L-LTD • ‘Tagging’ • Cross tagging.
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Neuronal plasticity Input 1 Input 2 Output
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LTP in hippocampal slices Associative and input specific
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LTP mechanics I Figure by MIT OpenCourseWare
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LTP mechanics II Figure by MIT OpenCourseWare
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L-LTP and L-LTD require protein synthesis LTP L-LTP
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How do the proteins know where to go? Input 1
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Unformatted text preview: Input 2 Output Tagging Input 1 Input 2 Output Cross tagging Setting a tag Creating PRPs – plasticity related proteins ‘capturing’ PRPs Last big assignment • Will be about tagging. • Will be described next week. Next week’s questions • Sajikumar et al. – How would you test if a compound inhibits LTP induction or maintenance? • Kauderer and Kandel – What stimulation protocol is sufficient for setting an LTD ‘Tag’?...
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This note was uploaded on 11/11/2011 for the course BIO 7.344 taught by Professor Bobsauer during the Spring '08 term at MIT.

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Lecture9 - Input 2 Output Tagging Input 1 Input 2 Output...

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