Alternative methods for library generationLai, Y.-P.; Huang, J.; Wang, L.-F.; Li, J.; Wu, Z.-J. A new approach to random mutagenesisin vitro. Biotech. Bioeng. 2004, 86, 622-627.Coia, G.; Ayres, A.; Lilley, G.G.; Hudson, P.J.; Irving, R.A. Use ofmutator cells as a means for increasing production levels of a recombinant antibody directed against Hepatitis B. Gene1997, 201, 203-209.
Chemical mutagenesis•How does mutagenesis occur? What do the authors use this method to study?•What are the results?•What are the benefits to using this method? •Are there any pitfalls to this method? SOOOH3CEMS
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