cogcontrol

cogcontrol - Progressive Loss of Dopamine Neurons Depletion...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon
Cognitive Control Processes and Working Memory in Parkinson’s Disease (PD)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Early Stage Idiopathic PD 1. Rigidity 2. Tremor 3. Bradykinesia - extreme slowness of movement Motor Symptoms
Background image of page 2
Core Pathological Hallmark Progressive loss of dopamine (DA) neurons in the ventrolateral tier of the substantia nigra pars compacta which primarily projects to the dorsal striatum
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Severe SNpc DA Neuron Loss in PD Cortex Striatum Pallidum SNr Thalamus
Background image of page 4