fall05lectu7_lar

fall05lectu7_lar - 7.18 Day 7 Agenda...

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7.18 Day 7 Agenda introduction/background and significance
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provides context, focus, and justification of the project gives critical background information of the main elements of the project (e.g., disease, genes, protein) for the non-expert reader concisely reviews and stresses importance of past primary research papers most relevant to the project highlights deficiencies in current knowledge or understanding shows how references provide intellectual foundation of the project tell a story: start with the general area and questions, then narrow to the topic area
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Example of an Introduction Text of example introduction removed. Please see the Introduction for the following paper: Chatelain, F. C., N. Alagem, Q. Xu, R. Pancaroglu, E. Reuveny, and D. L. Minor, Jr. “The pore helix dipole has a minor role in inward rectifier channel function.” Neuron 47, no. 6 (Sep 15, 2005): 833-43. • This introduction provides background information about the state of knowledge about potassium channels, ion selectivity, role of pore helix in ion selectivity. • Introduction does a nice job of going from the general to the specific, in about 2 double-spaced pages: First paragraph: ion channels, role in electrical signaling Second paragraph: potassium channels, ion selectivity Third paragraph: pore helix • The introduction also shows how references provide an intellectual foundation for their experiments.
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Background and Significance Briefly sketch the background leading to the present application, critically evaluate existing knowledge, and specifically identify the gaps that the project is intended to fill. State concisely the importance and health
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This note was uploaded on 11/11/2011 for the course BIO 7.012 taught by Professor Lander during the Fall '10 term at MIT.

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fall05lectu7_lar - 7.18 Day 7 Agenda...

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