guideline - • Are the experimental approaches appropriate...

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Reading research papers- some guidelines In reading papers, it is useful to ask the following: What is the background to the paper- that is, the historical context? What was known before the present study was performed? What is the broad question that the authors wish to ask- for example, how does the embryo decide to form a neural tube? What is the specific question that the authors ask- for example, what is the role of the actin gene in regulating neural tube formation? What hypotheses are proposed and tested? What experimental approach is taken to ask the specific hypotheses? That is, for each figure what experiments were performed? What aspect of the specific question does each experiment address?
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Unformatted text preview: • Are the experimental approaches appropriate, or would some other approach have been more definitive? • Have appropriate controls been performed? • Are you convinced by the conclusions that the authors draw from each experiment? • Are the hypotheses made supported or not supported? • Have the authors answered the specific question they set out to? Do you think they have contributed a substantial or just a small increase to understanding the broad question? • What experiments would logically follow from this study? Massachusetts Institute of Technology Department of Biology 7.22, Fall 2005 - Developmental Biology Instructors: Professor Hazel Sive, Professor Martha Constantine-Paton...
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This note was uploaded on 11/11/2011 for the course BIO 7.012 taught by Professor Lander during the Fall '10 term at MIT.

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