ps1as05

ps1as05 - MIT Department of Biology 7.013: Introductory...

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NAME________________________________TA______________Section #______ 1 7.013 Spring 2005 Problem Set 1Solutions FRIDAY February 11, 2004 Problem sets will NOT be accepted late. Question 1 a) Circle the correct answer. i) Homo sapiens emerged ____________years ago. 5,000 50,000 500,000 5,000,000 50,000,000 ii) There are __________________billion letters (bases) in the human genome. one three thirty 3 hundred iii) An alpha helix is an example of _________________structure. primary secondary tertiary quarternary b) What are the four major types of biological molecules discussed in lecture? What monomers make up these molecules? Give one important function of each type of biological molecule in the cell. Name of molecule Monomer One function of the Polymer Lipid Fatty Acid, Triglyceride Hormones, Membranes, Energy storage Nucleic Acids Nuceleotide Carry information Carbohaydrate Sugar Energy, Protein Modification, Protein Amino Acid Enzymes, motility, structural roles MIT Department of Biology 7.013: Introductory Biology - Spring 2005 Instructors: Professor Hazel Sive, Professor Tyler Jacks, Dr. Claudette Gardel
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2 c) Name the molecules depicted below. O CH 2 O P O N N N N NH 2 O H H O - - H H H O P O O - O H H O H C 2 H H adenine thymine H O P O O - O H H H C 2 HO H N HN O O N N N N NH 2 adenine CH 3 DNA O CH 2 O P O N N N N NH 2 O O - - H H O P O O - O H H O H C 2 H H adenine uracil O P O O - O H H O H C 2 HO H H N HN O O N N N N NH 2 adenine OH OH OH C C C C COO C C C O N H N N N CH H H H O O (CH ) (CH ) C C O O NH + CH CH H C H H H H NH C O NH NH + CH 3 3 2 2 2 2 2 2 2 2 3 3 RNA Protein d) Circle one peptide bond if there is any in the figures above. DNA RNA Peptide, protein, polypeptide
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3 Question 2 a) Draw the energy profile for this reaction. Refer to Chapter 6 in the textbook. A + B ---------> C + D Δ G o' = - 3.4 kcal/mol On the diagram be sure to… 1) show relative energy levels of the reactants and the products. 2) label the axes. 3) label reactants and products. 4) indicate the energy of activation. 5) indicate Δ G. Free Energy (G) kcals/mole fructose 6-phosphate + ATP fructose 1,6-bisphosphate + ADP Energy of activation Δ G= -3.4 kcals/mole Reaction Progress o b) An enzyme _____________ the activation energy of a reaction. lowers raises does not affect c) An enzyme _____________the Δ G of a reaction. lowers raises does not affect d) Using a dashed line in the above diagram, draw the energy profile in the presence of an enzyme.
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4 Question 3 Some receptors are transmembrane proteins found on the cell surface. CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 C O O C C O O C CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 H H H H 2 C O P O O O CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 C O O C C O O C CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 H H H H 2 C O P O O O CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH
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ps1as05 - MIT Department of Biology 7.013: Introductory...

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