ps3q_05

ps3q_05 - MIT Department of Biology 7.014 Introductory...

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MIT Department of Biology 7.014 Introductory Biology, Spring 2005 Name:______________________________________ Section :______ 7.014 Problem Set 3 Answers to this problem set are to be turned in. Problem sets will not be accepted late. Solutions will be posted on the web. Question 1 After acing the 7.014 Quiz 1, you take a well-deserved break and go “looking for Baker House.” Somewhere in the tunnels you stumble on a device you have never seen before, and start playing with its dials. It turns out to be a time- and reality-transporting device. It lands you in the office of the editor of the journal Nature in February of 1953. This is a reality much like our own, except that in this reality no one has yet seen Rosalind Franklin’s data. The editor is happy to see you, since he believes the knowledge you acquired in 7.014 will help him with the decision he must make. In front of him are four papers proposing various models for the structure of DNA. For each model below, indicate whether the editor should accept or reject the paper (i.e. whether the model is plausible or not) and explain your advice. If your advice is based on data the editor has not yet seen, explain what the data is and how it will affect the plausibility of the model. If your advice is based on data the editor is familiar with, explain how that data is either consistent or inconsistent with the model. i. Model A: DNA is a double-stranded helix with sugar-phosphate backbones in the center, and bases sticking out into solution. In this model, the strands are running anti-parallel to
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ps3q_05 - MIT Department of Biology 7.014 Introductory...

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