Bacterial Diseases of the Nervous SystemMicrobial diseases affecting the nervous system tend to be serious because of the critical functions performed by the brain, spinal cord, and peripheral and cranial nerves. Infections can occur in the nervous tissue or in the covering membranes called meninges. Diagnostic tests for diseases of the nervous system often involve examination of the cerebrospinal fluid, and antibiotic therapy must use drugs that pass the blood-brain barrier.Meningococcal meningitis. Meningococcal meningitis is caused by the Gram-negative diplococcus Neisseria meningitidis.This organism is called the meningococcus. It is transmitted by respiratory droplets and often inhabits the nasopharynx without evidence of disease. The organism is believed to possess endotoxins that account for the symptoms associated with meningitis. Patients suffer severe and debilitating headache, as well as fever, chills, and blue-black
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