Gen+Path+Exam+2+SG

Gen+Path+Exam+2+SG - Gen Path Exam 2 SG 1....

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Gen Path Exam 2 SG 1. Arteiolosclerosis: a. Hyaline: thickening of basement membrane a.i. Hypertension and diabetes mellitus b. Hyperplastic (proliferative): fibrocellular intimal thickening b.i. Malignant hypertension and scleroderma 2. Fibroelastic hyperplasia (proliferative arteriosclerosis): concentric smooth muscle cell proliferation and collagen deposition of the intima of small to medium-size muscular arteries. 3. Fatty streak : occurs in infants and children in atherosclerotic and nonatherosclerotic prone geographic areas. 4. Atheroma progressive changes include fissure formation. 5. Aneurysm is a complication of atherosclerosis. It is a formation due to pressure atrophy of the media with altered balance of collagen synthesis/degradation. 6. Acute myocardial infarction (Type of ischemic heart disease): a. Clinical presentation: chest pain, shortness of breath b. Diagnostic tests: ECG changes, c. Pathology: neutrophil infiltration 7. Myocarditis pathology includes a viral infection producing lymphocytic infiltrate with foci of necrosis. 8. Hypertrophic cardiomyopathy (a primary, genetic cardiomyopathy) a. Inappropriate (spontaneous) myocardial hypertrophy, asymmetric hypertrophy which is greater in the interventricular septum that the left ventricular free wall and often obstructs the left ventricular outflow tract. 9. Dilated Cardiomyopathy: a. Dilation of all 4 heart chambers 10. Tetralogy of Fallot: there is a ventricular septal defect, narrowing of the right ventricular outflow, overriding of the aorta over the right ventricular outflow and right ventricular hypertrophy. 11. Mitral Valve prolapse: severe prolapse is also called floppy mitral valve. 12. Aortic Valve Stenosis a. Fibrosis and calcification reduce the valve susp mobility. This can be due to chronic rheumatic valvular disease. 13. Infectious endocarditis: a. This is usually caused by a bacterial infection in a heart valve, although it may also be caused by fungus or other unusual infections. Predisposing factors include abnormal heart valves, prosthetic valves, IV drug use, intracardiac shunts and immunosuppression. b.
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This note was uploaded on 11/11/2011 for the course PATHOL 640 taught by Professor Barth,r during the Spring '08 term at Ohio State.

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Gen+Path+Exam+2+SG - Gen Path Exam 2 SG 1....

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