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Unformatted text preview: 4.0 Pharmacodynamics Directions:
1. Write your name and the date on your Scantron form. Identify the
subject as the course number (for example, RADT 101) along with
the test number (for example, Unit 1). 2. For each of the questions below, select the best answer to the
question. 3. Using a No. 2 pencil, fill in the appropriate answer on the answer
sheet. 4. Erase unwanted answers completely. Questions with two or more
filled in answer spaces are graded as incorrect. 5. Answer all questions. 6. You have a maximum 15 minutes to complete the following 25
questions. (Note this time factor approximates the amount of time
you would be allowed to answer the same number of questions on
the Registry examination in radiography) 1. What are the two processes that happen before a drug
reaches its sight of action.
E. Absorption and distribution.
Absorption and metabolism.
Distribution and elimination.
Elimination and absorption.
Metabolism and elimination. 2-6. Matching
Mechanism of Action
7. Which of the following is not a term generally used in
E. 8. Refers to what happens when two things meet and
Method by which a drug elicits (draws out, extracts)
Refers to drugs.
A specific biological site located on a cell surface or
within a cell, where specific drugs can attach to the
Study of how the effects of a drug are manifest. Onset of action
Termination of action
Therapeutic effect Which of the following is an interaction that drugs use to
E. Drug-receptor interaction.
Nonspecific drug interaction.
All of the above. 9-13. Matching
Potency A. A catalyst that is responsible for bringing forth
biochemical reactions throughout the body.
The relative concentration required to produce the
desired effect (how much dose is needed).
The degree to which a drug is able to produce the
desired effect (how great the effect will be).
Any organ or system in the body in which the desired
The propensity (tendency) of a drug to bind or attach
itself to a given receptor site. B.
14. Which of the following is not a drug-receptor interaction
D. 15. Competitive antagonist
Non competitive antagonist
Partial antagonist Which of the following is not a process responsible for the
amount of drugs that will reach and remain in the
Elimination 16-20. Matching:
20. Minimum effective concentration
Peak serum concentration
Half-life of elimination
Therapeutic Index A. The lowest plasma concentration that produces the
desired drug effect.
The range of plasma concentration that produces the
desired effect without the toxicity. B.
21. The highest plasma concentration attained from a
It is a measure of the relative safety of a drug.
The time required for the current serum drug
concentration to decline by 50%. Which of the following when altered, effects the stability of a
drugs half-life elimination.
both B & C
both A & C 4
22. What is the formula for the therapeutic index?
E. 23. Adverse effect
Synergistic response What is the relationship between toxicity and drug dose?
D. 25. LD50/ED50
LD51/ED51 A generally predictable pharmacologic action on body
systems other than the action intended defines ___________.
E. 24. TI=
TI= The lower the dose, the greater the toxic effect.
The higher the dose, the lower the toxic effect.
The higher the dose, the greater the toxic effect.
There is no relationship between the dose and toxicity. The result of two drugs acting together to give a
pharmacologic response that is greater than the response
that is expected is known as ___________________.
C. Adverse effect
Synergistic response ...
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- Spring '11