RADT_150_Unit_4_Exam - 4.0 Pharmacodynamics Directions 1...

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Unformatted text preview: 4.0 Pharmacodynamics Directions: 1. Write your name and the date on your Scantron form. Identify the subject as the course number (for example, RADT 101) along with the test number (for example, Unit 1). 2. For each of the questions below, select the best answer to the question. 3. Using a No. 2 pencil, fill in the appropriate answer on the answer sheet. 4. Erase unwanted answers completely. Questions with two or more filled in answer spaces are graded as incorrect. 5. Answer all questions. 6. You have a maximum 15 minutes to complete the following 25 questions. (Note this time factor approximates the amount of time you would be allowed to answer the same number of questions on the Registry examination in radiography) 1. What are the two processes that happen before a drug reaches its sight of action. A. B. C. D. E. Absorption and distribution. Absorption and metabolism. Distribution and elimination. Elimination and absorption. Metabolism and elimination. 2-6. Matching 2. 3. 4. 5. 6. Pharmaco Dynamic Pharmacodynamics Mechanism of Action Receptor 2 A. B. C. D. E. 7. Which of the following is not a term generally used in pharmacodynamics. A. B. C. D. E. 8. Refers to what happens when two things meet and interact. Method by which a drug elicits (draws out, extracts) effects. Refers to drugs. A specific biological site located on a cell surface or within a cell, where specific drugs can attach to the body. Study of how the effects of a drug are manifest. Onset of action Distribution Toxicity Termination of action Therapeutic effect Which of the following is an interaction that drugs use to produce effects. A. B. C. D. E. Drug-receptor interaction. Drug-enzyme interaction. Nonspecific drug interaction. Drug-drug interaction. All of the above. 9-13. Matching 9. 10. 11. 12. 13. Affinity Target organ Enzyme Efficacy Potency A. A catalyst that is responsible for bringing forth biochemical reactions throughout the body. The relative concentration required to produce the desired effect (how much dose is needed). The degree to which a drug is able to produce the desired effect (how great the effect will be). Any organ or system in the body in which the desired effect occurs. The propensity (tendency) of a drug to bind or attach itself to a given receptor site. B. C. D. E. 3 14. Which of the following is not a drug-receptor interaction term. A. B. C. D. 15. Competitive antagonist Non competitive antagonist Impartial agonist Partial antagonist Which of the following is not a process responsible for the amount of drugs that will reach and remain in the circulatory system. A. B. C. D. E. Consumption Absorption Distribution Metabolism Elimination 16-20. Matching: 16 17. 18. 19. 20. Minimum effective concentration Peak serum concentration Therapeutic range Half-life of elimination Therapeutic Index A. The lowest plasma concentration that produces the desired drug effect. The range of plasma concentration that produces the desired effect without the toxicity. B. C. D. E. 21. The highest plasma concentration attained from a dose. It is a measure of the relative safety of a drug. The time required for the current serum drug concentration to decline by 50%. Which of the following when altered, effects the stability of a drugs half-life elimination. A. B. C. D. E. Alcohol Metabolism Excretion both B & C both A & C 4 22. What is the formula for the therapeutic index? A. B. C. D. E. 23. Adverse effect Allergic reaction Side effect Drug-drug interaction Synergistic response What is the relationship between toxicity and drug dose? A. B. C. D. 25. LD50/ED50 ED50/LD50 ED49/LD49 LD49/ED49 LD51/ED51 A generally predictable pharmacologic action on body systems other than the action intended defines ___________. A. B. C. D. E. 24. TI= TI= TI= TI= TI= The lower the dose, the greater the toxic effect. The higher the dose, the lower the toxic effect. The higher the dose, the greater the toxic effect. There is no relationship between the dose and toxicity. The result of two drugs acting together to give a pharmacologic response that is greater than the response that is expected is known as ___________________. A. B. A. B. C. Adverse effect Side effect Allergic reaction Drug-drug interaction Synergistic response ...
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