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ZOL_320_Lecture_Study_guide_2 - ZOL 320 2011 Lecture Study...

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ZOL 320 2011 Lecture Study Guide 2 Readings: Chapter 2 The Cellular and Genetic Base of Development pp. 1-16, 31-35, 39-43, 53-57,79-84 Define, describe or illustrate the following terms: Cells and Development : Epithelial cell cells that have a formation, usually layers. Ex: skin Phospholipid make up the membrane, can self assemble in water signal transduction Polypeptide growth factors : FGF (Fibroblast growth factor): discovered in serum and needed for growth of some cells Wingless (WNT): found first in fly mutants and later in breast cancers Sonic Hedgehog (SHH): originally found as a fly gene affecting bristles. Transforming growth factor-beta : (TGF-beta): found released from cancer cells in culture to stimulate growth of normal cells Paracrine interactions: one cell produces and and a neighboring cell receives it. (ex. Polypeptide growth factors) stem cells germinative region wehre you make more cells but it still regulates how much you grow prospective fate determination before differentiation its when a cells fate is “fixed” Microtubules involved in cell shape Exploratory behavior Centriole (MTOC) where you make more cells but it still regulates how much you grow Asters Actin intermediate filaments cytokeratins: epithieal cells…makes up 80% of skin cell polarity Desmosome anchor epi. Cells together…very strong Integrin sticks to the fibronectin Laminin Proteoglycan negatively charged molecules that attract water and cause a tissue to swell to create space. Gap junction allows cells to communicate and organize development Tight junction used for sealing off compartments Indirect immunofluorescence Mesenchymal cell a sometimes motile cell with a fan-like, star-like or spindle shape lacking strong connections to neighboring cells Self-assembly protein kinase
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fibroblast growth factor hyperplasia contunious cell formation of variable duration blasts vs cytes embryotic dividing cells are blasts and differientied cells are cytes compensatory hyperplasia when something regrows after loss/damage apoptosis cytoskeleton α and β tubulin make up microtubules Colchicine Spindle Microfilaments Cytochalasin
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