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Lecture 21 SRR F-2011 - Biology 313 Lecture 21 ISU students...

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Biology 313 Lecture 21 Oct 14, 2011 ISU students hiking on Beach Cliffs to look at rocks and marine organisms (photo courtesy of Emily Vonderhaar, Bio 313 student). Mediterranean Sea Biol 394 in Spain (3 or 6 credits): ISU on the Mediterranean http://www.language.iastate.edu/valencia/
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Chapter 9: Chromosome Mutations 1. Chromosome morphology 2. Chromosome rearrangements A. Duplications B. Deletions C. Inversions D. Translocations 3. Aneuploidy 4. Polyploidy
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Chapter 9 : Chromosome Mutations (Problems) Problems Concept Checks 1, 2, 4 Worked Problems at the end of chapter: 1 Comprehension & Application Questions at end of Chapter: 1-6; 9, 11, 18, 19, 22, 24
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Chromosome mutations Variations in number and/or structure of chromosomes Three classes: Rearrangements Aneuploids Polyploids
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Review Ch. 2: Chromosome Morphology 2 arms equal length Long arm + knob (satellite) Centromere at end Long arm + short arm
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Chromosome Banding Staining helps distinguish chromosomes of similar morphology from one another General procedure: Make karyotype from dividing cells on a microscope slide, then stain the fixed chromosomes e.g., stain with G iemsa dye: it stains AT- rich regions, reveals G bands , and after staining longer, C -bands (c entromere bands)
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G bands (AT-rich) Giemsa staining for chromosme structure C bands c entromere
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Chapter 9: Chromosome Mutations 1. Chromosome morphology 2. Chromosome rearrangements A. Duplications B. Deletions C. Inversions D. Translocations 3. Aneuploidy 4. Polyploidy
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Rearrangements -Change structure of chromosome -4 types of rearrangements: Duplications Deletions Inversions Translocations
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