Lecture 25 SRR F-2011

Lecture 25 SRR F-2011 - Biology 313, Lecture 25 Oct 26,...

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Biol 394 in Spain (3 or 6 credits): ISU on the Mediterranean http://www.language.iastate.edu/valencia/ Biology 313, Lecture 25 Oct 26, 2011 ISU Life Science students at the turtle hospital in Valencia
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Chapter 10 : DNA– Chemical Nature of the Gene Problems (through Section 10.3) Concept Checks: 1-8 Worked Problems: 1 Comprehension and Application Questions at end of Chapter: 1-14, 17-21, 24, 25, 27, 28, 31-34 (19, 21, 22, 23 answers in “Assignments” on Blackboard)
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Questions of Hershey and Chase: -- How does the T2 lytic cycle work? -- How do phage reproduce in bacteria? -- Is protein or DNA the genetic material? CONCLUSION: DNA, and not protein, enters the bacterial cell during bacteriophage infection and directs viral reproduction. This means that DNA is the genetic material!
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Lytic Cycle of T2 phage (as known today, not pre-1950’s!)
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Hershey: Nobel Prize in 1969, Why not Martha Chase? Hershey-Chase Experiment: Conclusions You can do your “extra credit” paper on Martha Chase
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Chapter 10 : DNA– Chemical Nature of the Gene 1. Characteristics of genetic material 2. Early studies of DNA: what is it? 3. Early evidence that DNA is the genetic material A. The “transforming principle” B. Hershey-Chase 4. RNA as the genetic material 5. Structure of DNA
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RNA as the genetic material -- Heinz Fraenkel-Conrat and Bea Singer (1956): experiments with tobacco mosaic virus ( TMV ), the first virus to be discovered -- TMV is a single stranded RNA virus that is enclosed in a protein coat ( capsid ). It infects cells of tobacco leaves, and progeny TMV are produced in the cells using plant cell metabolites (e.g., amino acids, nucleotides) and machinery for translating proteins (ribosomes).
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-- TMV is transmitted to neighboring cells via plasmodesmata (channels between cells in apposing cell walls).
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Lecture 25 SRR F-2011 - Biology 313, Lecture 25 Oct 26,...

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