lect20 - These enzymes are in different cell compartments 3...

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1 2 3 1 2 3 In liver, PK inhibited by phosphorylation These enzymes are in different cell compartments
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Membrane energetics and dynamics
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The fluid mosaic model for membranes
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Membranes present a barrier to free diffusion, especially for polar molecules. The flux, mass/area/time, by simple diffusion, is proportional to the diffusion coefficient for the molecule in question and the concentration gradient (Fick’s Law) J a = P a C a Here we replace D with a permeability constant, P, that is D/x, for a “standard” membrane thickness. mmol/cm 2 s = cm/s • mmol/cm 3
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Simple Diffusion J A [A out ]-[A in ]
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Membrane transport • Simple diffusion (governed by concentration gradient) • Facilitated diffusion (governed by concentration gradient, but faster to equilibrium) • Active transport (uses energy source to “pump” against gradient)
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Transporter Terms
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This note was uploaded on 11/16/2011 for the course CH 370 taught by Professor Hackert during the Spring '08 term at University of Texas at Austin.

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lect20 - These enzymes are in different cell compartments 3...

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