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lecture_10_03_11 - II.C How does voltage change in a neuron...

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x=0 μ m time 0 250 500 distance ( μ m) Stimulus 250 μ m 250 μ m rec 1 at 0 μ m rec 2 at 250 μ m rec 3 at 500 μ m time time What properties of a neuron are responsible for voltage dropping (attenuating) as a function of space? II.C. How does voltage change in a neuron as we get further away from the injection point? We can record voltage at remote locations We can model the influx of sodium as a current source & the recording electrodes as voltmeters Δ Vf inal at x = 250 μ m II.C.1. What does the voltage change over space look like for a step injection of current II.C.2 What causes the voltage to attenuate as you record further from the injection point? Internal resistance The internal environment of a neuron offers resistance to ion movement Membrane resistance The membrane has protein channels that allow ions to escape When taken together, both the internal and membrane resistance lead to voltage attenuation in space Δ Vf inal at x = 500 μ m Voltage change at time = Voltage change at time =
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