Lecture 26c BioMEMS

Lecture 26c BioMEMS - Photomicrograph of a 2020 array of...

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Microsurgery, Microneedles, and Drug Delivery Dr. Bruce K. Gale Focused Ion Beam Machining Microsurgical Tools Surgical Tools • Ultrasound transducers for cutting • Piezoresistors for control and setup of gradients • Thin films for cutting – Can be nm in thickness • Less than cell size – No blunt tip Drug Delivery Rates
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Microneedles • Microneedles allow collection and dispensing of microsamples • Large array required to dispense and collect necessary volumes • Packaging the primary limitation Microneedles LIGA Microneedles 200 µ m Planar Microneedle Array
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Unformatted text preview: Photomicrograph of a 2020 array of solid microneedles resting on a human finger to give a sense of its small size. Planar Needle Array An SEM image of a portion of an array showing sharp and uniform needles Typically polysilicon Can be atomically sharp if made using self occluding mask Reservoirs for Drug Delivery Caps for Drug Release Implantable Controlled Capsule Long term, controlled drug release Holes open to allow drug to diffuse out Modified version incorporates piston...
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This note was uploaded on 11/16/2011 for the course MSE 5960 taught by Professor Douglas during the Fall '04 term at University of Florida.

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Lecture 26c BioMEMS - Photomicrograph of a 2020 array of...

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