Lecture17

Lecture17 - 02.24.10 Lecture 17 - Cell motility The Range...

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Unformatted text preview: 02.24.10 Lecture 17 - Cell motility The Range of Cell Movement Velocities of moving cells span more than 4 orders of magnitude Each cell has evolved the speed and mechanism of its migration to match: Developmental programs The cells unique energy requirements The way the cell acquires nutrients The direction of cell migration -taxis -Cell movement according to an environmental cue Can be an attracting or repelling signal Kinds of signals Chemotaxis - soluble factor (molecule or protein) Haptotaxis - same as chemotaxis, but the signal is immobilize on a surface Durotaxis - rigidity of the cells substrate -Taxis, a form of cell signaling 1. Reception of signal 2. Transduction of signal 3. Cellular response Cell motility towards or away from the signal Cellular locomotion is an essential part of life for many organisms ingle celled protozoa - ictyostelium discoideum http://www.youtube.com/watch?v=VWGA7kIeE0Q Cellular locomotion is an essential part of life for many organisms Single celled protozoa - Dictyostelium discoideum http://www.youtube.com/watch?v=VWGA7kIeE0Q Mahadeo and Parent, 2006 QuickTime and a Photo decompressor are needed to see this picture. Embryonic development in animals Movements of autonomous cells or specialized cellular structures QuickTime and a Photo decompressor are needed to see this picture. Cellular locomotion is an essential part of life for many organisms arly development - neurons igrating from their point of origin to heir developmental destination Later Development - Once the neurons have found their home within the cerebral cortex they send out axons that stretch into other parts of the brain Chemoattractant Chemorepellent QuickTime and a...
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This note was uploaded on 11/18/2011 for the course MATH 383H taught by Professor Euler during the Spring '08 term at UNC.

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Lecture17 - 02.24.10 Lecture 17 - Cell motility The Range...

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