Problems-4-answers

Problems-4-answers - Biology 205: Problem Set for Lectures...

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Biology 205: Problem Set for Lectures 9, 10, and 11 1. Name the three primary cytoskeletal filaments in order of decreasing diameter. A. Microtubules B. Intermediate filaments C. Actin filaments (microfilaments) 2. Receptor-activated G-proteins interact with a variety of downstream effectors such as adenylyl cyclase and Phospholipase C. What second messenger molecule(s) is/are generated by activation of phospholipase C and what is/are the downstream effector(s)? Inositol trisphosphate (IP3), which causes the release of calcium from internal stores in the ER, and diacylglycerol (DAG). The combined effect of a calcium transient and DAG production is to activate protein kinase C and recruit it to the membrane for phosphorylation of its downstream targets. 3. Of the two types of signaling molecules we discussed in class (large hydrophillic ligands and small or hydrophobic molecules), which mediates the most direct signaling pathway and why? Steroids and NO.
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Problems-4-answers - Biology 205: Problem Set for Lectures...

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