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FSN420.writteneval15 - FSN 420 paper evaluation form cohort...

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FSN 420 paper evaluation form cohort studies Kim Chin Study (author, date): Michel Lucas, 2011 Research Question (What is it? Clearly stated? Is there a hypothesis?): “During this 10-year study, what is the relation between different n-3 and n-6 types with clinical depression incidence?” Yes, this was clearly stated. The hypothesis wasn’t clearly stated, but it made it seem that they wanted to carry out another study to clarify that n-3 and n-6 decreases the incidence of clinical depression, since the previous 3 cohort studies did not agree amongst each other. Design (brief summary of how study was carried out, including a graphical representation as in class and readings): Since previously in only 3 cohort studies, results have been inconsistent, and had a need for a larger sample size, a need for more than just a single dietary intake assessment at baseline, and a longer follow- up. In this 10 year observational cohort study, information on diet was obtained from validated food frequency questionnaires. US women from the Nurses’ Health study who were 50-77 years old and free from depressive symptoms at baseline were used in this 10 year follow up study to see if depression arised. Clinical depression was defined as reporting both physician-diagnosed depression and regular antidepressant medication use. Subjects (What are inclusion and exclusion criteria? Were they appropriate? Were health, demographics, and other characteristics of subjects described? Were the subjects a representative sample of the relevant target population of interest? Was selection of study group(s) free from bias? What was sample size?): The Nurses’ Health Study started with a prospective cohort of 121,700 registered female nurses aged 30- 55 y at enrollment and lives in 11 states of the United States. The cohort was contacted every 2 years with mailed questionnaires about lifestyle and medical history, which update exposure information and inquire about newly diagnosed medical illnesses. They excluded women who left more than 11 food items blank
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